2025
Cavanaugh, Chloe et al. “Effect of Host Telomerase Inhibition on Human Cytomegalovirus..” Journal of virology (2025): e0157824.
Hidalgo, Paloma. “The Protein Composition of Human Adenovirus Replication Compartments..” mBio 16.1 (2025): e0214424.
Justice, Joshua et al. “Multi-Epitope Immunocapture of Huntingtin Reveals Striatum-Selective Molecular Signatures..” Molecular systems biology (2025): n. pag.
Kostas, James, Colter Brainard, and Ileana M Cristea. “A Primer on Proteomic Characterization of Intercellular Communication in a Virus Microenvironment..” Molecular & cellular proteomics : MCP (2025): 100913.
Liu, Dawei, Timothy Howard, and Ileana M Cristea. “ATAC-Seq for Characterizing Host and Pathogen Genome Accessibility During Virus Infection..” Methods in molecular biology (Clifton, N.J.) 2866 (2025): 111–122.
Needham, J et al. “Ribosomal Protein S25 Promotes Cell Cycle Entry for a Productive BK Polyomavirus Infection..” Philosophical transactions of the Royal Society of London. Series B, Biological sciences 380.1921 (2025): 20230390.
Tyl, Matthew D, Victoria Merengwa, and Ileana M Cristea. “Infection-Induced Lysine Lactylation Enables Herpesvirus Immune Evasion..” Science advances 11.2 (2025): eads6215.
2024
Boyd, Jeffrey et al. “Fpa (YlaN) Is an iron(II) Binding Protein That Functions to Relieve Fur-Mediated Repression of Gene Expression in ..” mBio (2024): e0231024.
Chanin, Rachael B et al. “Intragenic DNA Inversions Expand Bacterial Coding Capacity.” Nature 634 (2024): 234–242. Print.
Emerson, James et al. “X-Chromosome-Linked MiRNAs Regulate Sex Differences in Cardiac Physiology..” Circulation research (2024): n. pag.
Hofstadter, William, Elene Tsopurashvili, and Ileana M Cristea. “Viral Regulation of Organelle Membrane Contact Sites..” PLoS biology 22.3 (2024): e3002529.
Hofstadter, William et al. “Infection-Induced Peripheral Mitochondria Fission Drives ER Encapsulations and Inter-Mitochondria Contacts That Rescue Bioenergetics..” Nature communications 15.1 (2024): 7352.
Hofstadter, William et al. “HCMV Strain- and Cell Type-Specific Alterations in Membrane Contact Sites Point to the Convergent Regulation of Organelle Remodeling..” Journal of virology (2024): e0109924.
Justice, Joshua et al. “DNA-PK and ATM Drive Phosphorylation Signatures That Antagonistically Regulate Cytokine Responses to Herpesvirus Infection or DNA Damage..” Cell systems 15.4 (2024): 339–361.e8.
Kichuk, Therese et al. “Using MitER for 3D Analysis of Mitochondrial Morphology and ER Contacts..” Cell reports methods 4.1 (2024): 100692.
Liu, Dawei, Jinhang Yang, and Ileana M Cristea. “Liquid-Liquid Phase Separation in Innate Immunity..” Trends in immunology (2024): n. pag.
Liu, Xiaonan et al. “Mapping Protein-Protein Interactions by Mass Spectrometry..” Mass spectrometry reviews (2024): n. pag.
Lum, Krystal et al. “Differential Contributions of Interferon Classes to Host Inflammatory Responses and Restricting Virus Progeny Production..” Journal of proteome research (2024): n. pag.
Reed, Tavis J et al. “Tapioca: A Platform for Predicting De Novo Protein-Protein Interactions in Dynamic Contexts..” Nature methods 21.3 (2024): 488–500.
2023
Betsinger, Cora N. et al. “Sirtuin 2 Promotes Human Cytomegalovirus Replication by Regulating Cell Cycle Progression.” mSystems 8 (2023): 00510–23.
Edwards, Whitney et al. “Quantitative Proteomic Profiling Identifies Global Protein Network Dynamics in Murine Embryonic Heart Development..” Developmental cell 58.12 (2023): 1087–1105.e4.
Liu, Dawei et al. “IFI16 Phase Separation via Multi-Phosphorylation Drives Innate Immune Signaling..” Nucleic acids research 51.13 (2023): 6819–6840.
McCollum, Chloe et al. “The Viral Packaging Motor Potentiates Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression Late in Infection..” PLoS pathogens 19.4 (2023): e1011163.
Park, Ji, Matthew D Tyl, and Ileana M Cristea. “Orchestration of Mitochondrial Function and Remodeling by Post-Translational Modifications Provide Insight into Mechanisms of Viral Infection..” Biomolecules 13.5 (2023): n. pag.
Song, Bokai et al. “Intercellular Communication Within the Virus Microenvironment Affects the Susceptibility of Cells to Secondary Viral Infections..” Science advances 9.19 (2023): eadg3433.
2022
Cook, Katelyn C et al. “Restructured Membrane Contacts Rewire Organelles for Human Cytomegalovirus Infection.” Nature communications 13 (2022): 4720.
Greco, Todd et al. “Dynamics of Huntingtin Protein Interactions in the Striatum Identifies Candidate Modifiers of Huntington Disease.” Cell Syst. 13.4 (2022): 304–320.e5. Print.
Howard, Timothy R. et al. “The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection.” mSystems 7 (2022): 00198–22.
Justice, Joshua L., and Ileana M. Cristea. “Nuclear Antiviral Innate Responses at the Intersection of DNA Sensing and DNA Repair.” Trends in Microbiology 30 (2022): 1056–1071.
Kennedy, Michelle A. et al. “A TRUSTED Targeted Mass Spectrometry Assay for Pan-Herpesvirus Protein Detection.” Cell Reports 39.6 (2022): 110810.
Kennedy, Michelle A. et al. “HTT-OMNI: A Web-Based Platform for Huntingtin Interaction Exploration and Multi-Omics Data Integration.” Molecular & Cellular Proteomics 21 (2022): 100275.
Robbe, Zachary et al. “CHD4 Is Recruited by GATA4 and NKX2-5 to Repress Noncardiac Gene Programs in the Developing Heart.” Genes Dev. 36.7-8 (2022): 468–482. Print.
Serrero, Manutea et al. “The Interferon-Inducible GTPase MxB Promotes Capsid Disassembly and Genome Release of Herpesviruses.” Elife 11 (2022): e76804. Print.
Tyl, Matthew, Cora Betsinger, and Ileana Cristea. “Virus–host Protein Interactions As Footprints of Human Cytomegalovirus Replication.” Current Opinion in Virology 52 (2022): 135–147.
2021
Betsinger, Cora N. et al. “The Human Cytomegalovirus Protein pUL13 Targets Mitochondrial Cristae Architecture to Increase Cellular Respiration During Infection.” Proceedings of the National Academy of Sciences 118.32 (2021): e2101675118.
Esposito, Mark et al. “TGF-β-Induced DACT1 Biomolecular Condensates Repress Wnt Signalling to Promote Bone Metastasis.” Nat Cell Biol 23.3 (2021): 257–267.
Howard, Timothy et al. “The DNA Sensor IFIX Drives Proteome Alterations To Mobilize Nuclear and Cytoplasmic Antiviral Responses, With Its Acetylation Acting As a Localization Toggle.” mSystems 6.3 (2021): e0039721.
Justice, Joshua et al. “Systematic Profiling of Protein Complex Dynamics Reveals DNA-PK Phosphorylation of IFI16 En Route to Herpesvirus Immunity.” Sci Adv 7.25 (2021): n. pag.
Lum, Krystal, and Ileana Cristea. “Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection.” Curr Issues Mol Biol 42 (2021): 635–686.
Murray-Nerger, Laura et al. “Lamin B1 Acetylation Slows the G1 to S Cell Cycle Transition through Inhibition of DNA Repair.” Nucleic Acids Res 49.4 (2021): 2044–2064.
Murray-Nerger, Laura, and Ileana Cristea. “Lamin Post-Translational Modifications: Emerging Toggles of Nuclear Organization and Function.” Trends Biochem Sci (2021): n. pag.
Sheng, Xinlei, and Ileana Cristea. “The Antiviral Sirtuin 3 Bridges Protein Acetylation to Mitochondrial Integrity and Metabolism During Human Cytomegalovirus Infection.” PLoS Pathog 17.4 (2021): e1009506.
Shi, Wei et al. “Cardiac Proteomics Reveals Sex Chromosome-Dependent Differences Between Males and Females That Arise Prior to Gonad Formation.” Developmental Cell 56.21 (2021): 3019–3034.e7.
Song, Bokai et al. “Post-Translational Modification Control of Viral DNA Sensors and Innate Immune Signaling.” Adv Virus Res 109 (2021): 163–199.
2020
Adhikari, Subash et al. “A High-Stringency Blueprint of the Human Proteome.” Nat Commun 11.1 (2020): 5301.
Federspiel, Joel et al. “Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA.” Cell Rep 32.4 (2020): 107943.
Greco, Todd, Michelle Kennedy, and Ileana Cristea. “Proteomic Technologies for Deciphering Local and Global Protein Interactions.” Trends Biochem Sci 45.5 (2020): 454–455.
Hartenian, Ella et al. “RNA Decay During Gammaherpesvirus Infection Reduces RNA Polymerase II Occupancy of Host Promoters But Spares Viral Promoters.” PLoS Pathog 16.2 (2020): e1008269.
Hashimoto, Yutaka et al. “Temporal Dynamics of Protein Complex Formation and Dissociation During Human Cytomegalovirus Infection.” Nat Commun 11.1 (2020): 806.
Howard, Timothy, and Ileana Cristea. “Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective.” Biomolecules 10.12 (2020): n. pag.
Additional publications and collaborations
Contact
Cristea Lab
Department of Molecular Biology
210 Thomas Laboratory
Washington Road
Princeton, NJ 08544
p 609-258-9425
Faculty Assistant
Mary Gidaro
[email protected]
105 Thomas Laboratory
p 609-258-8956
f 609-258-1704
Lab Website
molbiolabs.princeton.edu/cristea