2024
Kichuk, Therese et al. “Using MitER for 3D Analysis of Mitochondrial Morphology and ER Contacts..” Cell reports methods 4.1 (2024): 100692.
Reed, Tavis J. et al. “Tapioca: A Platform for Predicting De Novo Protein-Protein Interactions in Dynamic Contexts.” Nat Methods (2024): n. pag. Print.
2023
Betsinger, Cora N. et al. “Sirtuin 2 Promotes Human Cytomegalovirus Replication by Regulating Cell Cycle Progression.” mSystems 8 (2023): 00510–23.
Edwards, Whitney et al. “Quantitative Proteomic Profiling Identifies Global Protein Network Dynamics in Murine Embryonic Heart Development..” Developmental cell 58.12 (2023): 1087–1105.e4.
Liu, Dawei et al. “IFI16 Phase Separation via Multi-Phosphorylation Drives Innate Immune Signaling..” Nucleic acids research 51.13 (2023): 6819–6840.
McCollum, Chloe et al. “The Viral Packaging Motor Potentiates Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression Late in Infection..” PLoS pathogens 19.4 (2023): e1011163.
Park, Ji, Matthew D Tyl, and Ileana M Cristea. “Orchestration of Mitochondrial Function and Remodeling by Post-Translational Modifications Provide Insight into Mechanisms of Viral Infection..” Biomolecules 13.5 (2023): n. pag.
Song, Bokai et al. “Intercellular Communication Within the Virus Microenvironment Affects the Susceptibility of Cells to Secondary Viral Infections..” Science advances 9.19 (2023): eadg3433.
2022
Cook, Katelyn C et al. “Restructured Membrane Contacts Rewire Organelles for Human Cytomegalovirus Infection.” Nature communications 13 (2022): 4720.
Greco, Todd et al. “Dynamics of Huntingtin Protein Interactions in the Striatum Identifies Candidate Modifiers of Huntington Disease.” Cell Syst. 13.4 (2022): 304–320.e5. Print.
Howard, Timothy R. et al. “The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection.” mSystems 7 (2022): 00198–22.
Justice, Joshua L., and Ileana M. Cristea. “Nuclear Antiviral Innate Responses at the Intersection of DNA Sensing and DNA Repair.” Trends in Microbiology 30 (2022): 1056–1071.
Kennedy, Michelle A. et al. “A TRUSTED Targeted Mass Spectrometry Assay for Pan-Herpesvirus Protein Detection.” Cell Reports 39.6 (2022): 110810.
Kennedy, Michelle A. et al. “HTT-OMNI: A Web-Based Platform for Huntingtin Interaction Exploration and Multi-Omics Data Integration.” Molecular & Cellular Proteomics 21 (2022): 100275.
Robbe, Zachary et al. “CHD4 Is Recruited by GATA4 and NKX2-5 to Repress Noncardiac Gene Programs in the Developing Heart.” Genes Dev. 36.7-8 (2022): 468–482. Print.
Serrero, Manutea et al. “The Interferon-Inducible GTPase MxB Promotes Capsid Disassembly and Genome Release of Herpesviruses.” Elife 11 (2022): e76804. Print.
Tyl, Matthew, Cora Betsinger, and Ileana Cristea. “Virus–host Protein Interactions As Footprints of Human Cytomegalovirus Replication.” Current Opinion in Virology 52 (2022): 135–147.
2021
Betsinger, Cora N. et al. “The Human Cytomegalovirus Protein pUL13 Targets Mitochondrial Cristae Architecture to Increase Cellular Respiration During Infection.” Proceedings of the National Academy of Sciences 118.32 (2021): e2101675118.
Esposito, Mark et al. “TGF-β-Induced DACT1 Biomolecular Condensates Repress Wnt Signalling to Promote Bone Metastasis.” Nat Cell Biol 23.3 (2021): 257–267.
Howard, Timothy et al. “The DNA Sensor IFIX Drives Proteome Alterations To Mobilize Nuclear and Cytoplasmic Antiviral Responses, With Its Acetylation Acting As a Localization Toggle.” mSystems 6.3 (2021): e0039721.
Justice, Joshua et al. “Systematic Profiling of Protein Complex Dynamics Reveals DNA-PK Phosphorylation of IFI16 En Route to Herpesvirus Immunity.” Sci Adv 7.25 (2021): n. pag.
Lum, Krystal, and Ileana Cristea. “Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection.” Curr Issues Mol Biol 42 (2021): 635–686.
Murray-Nerger, Laura et al. “Lamin B1 Acetylation Slows the G1 to S Cell Cycle Transition through Inhibition of DNA Repair.” Nucleic Acids Res 49.4 (2021): 2044–2064.
Murray-Nerger, Laura, and Ileana Cristea. “Lamin Post-Translational Modifications: Emerging Toggles of Nuclear Organization and Function.” Trends Biochem Sci (2021): n. pag.
Sheng, Xinlei, and Ileana Cristea. “The Antiviral Sirtuin 3 Bridges Protein Acetylation to Mitochondrial Integrity and Metabolism During Human Cytomegalovirus Infection.” PLoS Pathog 17.4 (2021): e1009506.
Shi, Wei et al. “Cardiac Proteomics Reveals Sex Chromosome-Dependent Differences Between Males and Females That Arise Prior to Gonad Formation.” Developmental Cell 56.21 (2021): 3019–3034.e7.
Song, Bokai et al. “Post-Translational Modification Control of Viral DNA Sensors and Innate Immune Signaling.” Adv Virus Res 109 (2021): 163–199.
2020
Adhikari, Subash et al. “A High-Stringency Blueprint of the Human Proteome.” Nat Commun 11.1 (2020): 5301.
Federspiel, Joel et al. “Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA.” Cell Rep 32.4 (2020): 107943.
Greco, Todd, Michelle Kennedy, and Ileana Cristea. “Proteomic Technologies for Deciphering Local and Global Protein Interactions.” Trends Biochem Sci 45.5 (2020): 454–455.
Hartenian, Ella et al. “RNA Decay During Gammaherpesvirus Infection Reduces RNA Polymerase II Occupancy of Host Promoters But Spares Viral Promoters.” PLoS Pathog 16.2 (2020): e1008269.
Hashimoto, Yutaka et al. “Temporal Dynamics of Protein Complex Formation and Dissociation During Human Cytomegalovirus Infection.” Nat Commun 11.1 (2020): 806.
Howard, Timothy, and Ileana Cristea. “Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective.” Biomolecules 10.12 (2020): n. pag.
Kennedy, Michelle, William Hofstadter, and Ileana Cristea. “TRANSPIRE: A Computational Pipeline to Elucidate Intracellular Protein Movements from Spatial Proteomics Data Sets.” J Am Soc Mass Spectrom 31.7 (2020): 1422–1439.
Kinoshita, Noriyuki et al. “Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR Erk2 Signaling Pathway During Embryogenesis.” Cell Rep 30.11 (2020): 3875–3888.e3.
Omenn, Gilbert et al. “Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project.” J Proteome Res 19.12 (2020): 4735–4746.
Song, Bokai et al. “The DNA Sensor CGAS Is Decorated by Acetylation and Phosphorylation Modifications in the Context of Immune Signaling.” Mol Cell Proteomics 19.7 (2020): 1193–1208.
Tanneti, Nikhila et al. “The Axonal Sorting Activity of Pseudorabies Virus Us9 Protein Depends on the State of Neuronal Maturation.” PLoS Pathog 16.12 (2020): e1008861.
2019
Betsinger, Cora, and Ileana Cristea. “Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions.” J Proteome Res 18.5 (2019): 1929–1938.
Bredrup, Cecilie et al. “A Tyrosine Kinase-Activating Variant Asn666Ser in PDGFRB Causes a Progeria-Like Condition in the Severe End of Penttinen Syndrome.” Eur J Hum Genet 27.4 (2019): 574–581.
Carabetta, Valerie et al. “YfmK Is an N-Lysine Acetyltransferase That Directly Acetylates the Histone-Like Protein HBsu in.” Proc Natl Acad Sci U S A 116.9 (2019): 3752–3757.
Cook, Katelyn et al. “Peroxisome Plasticity at the Virus-Host Interface.” Trends Microbiol 27.11 (2019): 906–914.
Cook, Katelyn, and Ileana Cristea. “Location Is Everything: Protein Translocations As a Viral Infection Strategy.” Curr Opin Chem Biol 48 (2019): 34–43.
Cristea, Ileana, and Kathryn Lilley. “Editorial Overview: Untangling Proteome Organization in Space and Time.” Curr Opin Chem Biol 48 (2019): A1-A4.
Cristea, Ileana et al. “Early-Career Scientists Shaping the World.” mSystems 4.3 (2019): n. pag.
Esposito, Mark et al. “Bone Vascular Niche E-Selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis.” Nat Cell Biol 21.5 (2019): 627–639.
Federspiel, Joel et al. “Hdac4 Interactions in Huntington’s Disease Viewed Through the Prism of Multiomics.” Mol Cell Proteomics 18.8 suppl 1 (2019): S92-S113.
Federspiel, Joel, and Ileana Cristea. “Considerations for Identifying Endogenous Protein Complexes from Tissue via Immunoaffinity Purification and Quantitative Mass Spectrometry.” Methods Mol Biol 1977 (2019): 115–143.
Federspiel, Joel et al. “Conservation and Divergence of Protein Pathways in the Vertebrate Heart.” PLoS Biol 17.9 (2019): e3000437.
Hashimoto, Yutaka et al. “Mechanical Force Induces Phosphorylation-Mediated Signaling That Underlies Tissue Response and Robustness in Xenopus Embryos.” Cell Syst 8.3 (2019): 226–241.e7.
Additional publications and collaborations
Contact
Cristea Lab
Department of Molecular Biology
210 Thomas Laboratory
Washington Road
Princeton, NJ 08544
p 609-258-9425
Faculty Assistant
Mary Gidaro
[email protected]
105 Thomas Laboratory
p 609-258-8956
f 609-258-1704
Lab Website
molbiolabs.princeton.edu/cristea