Blowing Off Steam: Virus Inhibition of cGAS DNA Sensing

Publication Year
2015

Type

Journal Article
Abstract

Detection of viral DNA is essential for eliciting mammalian innate immunity. However, viruses have acquired effective mechanisms for blocking host defense. Indeed, in this issue of Cell Host & Microbe, Wu et al. (2015) discover a herpesviral strategy for inhibiting the prominent host sensor of viral DNA, cGAS.

Journal
Cell Host Microbe
Volume
18
Issue
3
Pages
270-2
Date Published
09/2015
ISSN Number
1934-6069
Alternate Journal
Cell Host Microbe
PMID
26355212